はじめまして
私は、
循環器専門医・内科認定医・心臓リハビリテーション指導士などの資格を持ち、
医師歴は20年以上。
急性期の総合病院や循環器病センター、
大学病院などで循環器内科医として勤務し、
現在は地域の病院で訪問診療や健診読影などに携わっています。
プロフィール
名前
吉川 大治
Daiji YOSHIKAWA, MD, PhD
資格・学位
- 医師免許
- 医学博士
- 循環器専門医
- 認定内科医
- 心臓リハビリテーション指導士
所属学会
- 日本循環器学会
- 日本内科学会
- 日本心臓リハビリテーション学会
現職
- 藤田医科大学 医学部 客員准教授
- 地域病院にて訪問診療・健診読影を担当
- SuwaMEDICA（スワメディカ） 代表
SuwaMEDICA運営にあたって
これまでに、心筋梗塞・狭心症・心筋症・心不全・不整脈・高血圧症などの心臓病を中心に、
たくさんの患者さんを診てきました。
その一方で、健診などで**「心電図異常があります」「胸部レントゲンに異常あり」、
とだけ書かれた結果を見て、
不安を抱える方**も多くいらっしゃいます。
「これって放っておいて大丈夫なの？」
「受診した方がいい？」
「どこに行けばいいの？」
と迷われる姿を、現場でたびたび目にしてきました。
このブログでは、そんな方々に向けて、
心電図や胸部レントゲン検査に関する情報や病気に関する知識を、
できるだけわかりやすく噛み砕いて発信していきます。
※すべての記事は**【医療広告ガイドライン】に配慮して作成しておりますが、
あくまで参考情報としてご利用いただき必要に応じて医療機関を受診**してください。
主要査読論文（循環器領域）
Optical coherence tomography images of a coronary artery aneurysm in an infarct-related artery 6 months after bare-metal stent implantation.
Yoshikawa D, et al. JACC Cardiovasc Interv. 2010 Dec;3(12):1300-2. doi: 10.1016/j.jcin.2010.07.018.
Three-year prognosis of Japanese patients with ST-elevation myocardial infarction treated with sirolimus-eluting stents.
Yoshikawa D, et al. Coron Artery Dis. 2009 Sep;20(6):422-7. doi: 10.1097/MCA.0b013e32832fa92c.
Characteristics of in vivo images from an in-stent restenosis lesion of a saphenous vein graft after bare-metal stent implantation: Assessment using optical coherence tomography.
Yoshikawa D, et al. J Cardiol Cases. 2010 Jan 12;1(3):e151-e153. doi: 10.1016/j.jccase.2009.12.002.
Importance of oral fluid intake after coronary computed tomography angiography: an observational study.
Yoshikawa D, et al. Eur J Radiol. 2011 Jan;77(1):118-22. doi: 10.1016/j.ejrad.2009.07.011.
Impact of the low- to high-density lipoprotein cholesterol ratio on composition of angiographically ambiguous left main coronary artery plaque.
Yoshikawa D, et al. Circ J. 2011;75(8):1960-7. doi: 10.1253/circj.cj-11-0019.
Impact of the first-generation drug-eluting stent implantation on periprocedural myocardial injury in patients with stable angina pectoris.
Yoshikawa D, et al. J Cardiol. 2012 Oct;60(4):264-9. doi: 10.1016/j.jjcc.2012.05.008.
Comparison of tissue characteristic between left main and non-left main coronary artery lesions–assessment using integrated backscatter intravascular ultrasound.
Yoshikawa D, et al. Int J Cardiol. 2013 Jul 31;167(2):613-7. doi: 10.1016/j.ijcard.2012.10.086.
Morphologic characterization and quantification of superficial calcifications of the coronary artery–in vivo assessment using optical coherence tomography.
Yoshikawa D, et al. Nagoya J Med Sci. 2012 Aug;74(3-4):253-9.
Association of cardiorespiratory fitness with characteristics of coronary plaque: assessment using integrated backscatter intravascular ultrasound and optical coherence tomography.
Yoshikawa D, et al. Int J Cardiol. 2013 Jan 10;162(2):123-8. doi: 10.1016/j.ijcard.2011.05.047.
Association of plasma ω-3 to ω-6 polyunsaturated fatty acid ratio with complexity of coronary artery lesion.
Yoshikawa D, et al. Intern Med. 2012;51(9):1009-14. doi: 10.2169/internalmedicine.51.7162.
Relation of omega-3 fatty acid and C-reactive protein to peripheral artery disease in patients with coronary artery disease.
Yoshikawa D, et al. Heart Vessels. 2014 Jul;29(4):449-55. doi: 10.1007/s00380-013-0384-4.
Post-stress perfusion abnormalities detected on myocardial perfusion single-photon emission computed tomography predict long-term mortality after elective abdominal aortic aneurysm repair.
Yoshikawa D, et al. Circ J. 2013;77(5):1229-34. doi: 10.1253/circj.cj-12-1355.
Prescription patterns of oral anticoagulants for patients with non-valvular atrial fibrillation: experience at a Japanese single institution.
Yoshikawa D, et al. Heart Vessels. 2016 Jun;31(6):957-62. doi: 10.1007/s00380-015-0694-9.
Clinical Characteristics and Long-Term Outcomes of Hypertrophic Cardiomyopathy.
Yoshikawa D, et al. Int Heart J. 2015;56(4):415-20. doi: 10.1536/ihj.14-418.
Indoxyl sulfate, a uremic toxin, and carotid intima-media thickness in patients with coronary artery disease.
Yoshikawa D, et al. Int J Cardiol. 2013 Feb 20;163(2):214-6. doi: 10.1016/j.ijcard.2012.06.094.
Relation of plasma indoxyl sulfate levels and estimated glomerular filtration rate to left ventricular diastolic dysfunction.
Yoshikawa D, et al. Am J Cardiol. 2013 Mar 1;111(5):712-6. doi: 10.1016/j.amjcard.2012.11.025.
Plasma indoxyl sulfate and estimated glomerular filtration rate.
Yoshikawa D, et al. Circ J. 2014;78(10):2477-82. doi: 10.1253/circj.cj-14-0401.
他、査読論文一覧
- Antihypertensive efficacy and safety of the angiotensin receptor blocker azilsartan in elderly patients with hypertension.
Yoshikawa D, et al. Drug Chem Toxicol. 2017 Jan;40(1):110-114. doi: 10.1080/01480545.2016.1188301. - Persistent Excessive Electrocardiogram ST-segment Elevation in a Patient with a Takotsubo Syndrome: What Could be the Cause?
Yoshikawa D, et al. Intern Med. 2016;55(3):323. doi: 10.2169/internalmedicine.55.5549. - Impact of circulating cathepsin K on the coronary calcification and the clinical outcome in chronic kidney disease patients.
Yoshikawa D, et al. Heart Vessels. 2016 Jan;31(1):6-14. doi: 10.1007/s00380-014-0570-z. - Takotsubo cardiomyopathy with involvement of delayed-onset rhabdomyolysis and acute kidney injury after rosuvastatin treatment.
Yoshikawa D, et al. Intern Med. 2015;54(1):31-5. doi: 10.2169/internalmedicine.54.3239. - Impact of cigarette smoking on coronary plaque composition.
Yoshikawa D, et al. Coron Artery Dis. 2015 Jan;26(1):60-5. doi: 10.1097/MCA.0000000000000168. - Effects of polyunsaturated fatty acids on periprocedural myocardial infarction after elective percutaneous coronary intervention.
Yoshikawa D, et al. EuroIntervention. 2014 Nov;10(7):792-8. doi: 10.4244/EIJV10I7A138. - Prognostic impact of lipid contents on the target lesion in patients with drug eluting stent implantation.
Yoshikawa D, et al. Heart Vessels. 2014 Nov;29(6):761-8. doi: 10.1007/s00380-013-0430-2. - Impact of chronic obstructive pulmonary disease on composition of left main coronary artery plaque with intermediate stenosis.
Yoshikawa D, et al. Int J Cardiol. 2014 Jul 1;174(3):865-6. doi: 10.1016/j.ijcard.2014.04.223. - Novel preprocedural and acute-phase postprocedural predictive factors for contrast-induced kidney injury in CKD patients.
Yoshikawa D, et al. Int J Cardiol. 2014 Mar 15;172(2):e293-6. doi: 10.1016/j.ijcard.2013.12.193. - Recovery of flow-mediated vasodilatation after repetitive measurements is involved in early vascular impairment: comparison with indices of vascular tone.
Yoshikawa D, et al. PLoS One. 2014 Jan 2;9(1):e83977. doi: 10.1371/journal.pone.0083977. - Impact of the circadian rhythm on microvascular function in patients with ST-elevation myocardial infarction.
Yoshikawa D, et al. Int J Cardiol. 2013 Oct 12;168(5):4948-9. doi: 10.1016/j.ijcard.2013.07.106. - Differences in tissue characterization of restenotic neointima between sirolimus-eluting stent and bare-metal stent: integrated backscatter intravascular ultrasound analysis for in-stent restenosis.
Yoshikawa D, et al. Eur Heart J Cardiovasc Imaging. 2013 Oct;14(10):996-1001. doi: 10.1093/ehjci/jet003. - Diabetes with preserved renal function is an independent risk factor for renal function deterioration after coronary computed tomography angiography.
Yoshikawa D, et al. J Comput Assist Tomogr. 2013 Sep-Oct;37(5):750-4. doi: 10.1097/RCT.0b013e31829a49aa. - Impact of angiotensin II receptor blocker therapy (olmesartan or valsartan) on coronary atherosclerotic plaque volume measured by intravascular ultrasound in patients with stable angina pectoris.
Yoshikawa D, et al. Am J Cardiol. 2013 Aug 1;112(3):363-8. doi: 10.1016/j.amjcard.2013.03.038. - Sirolimus- vs. paclitaxel-eluting stent to coronary intervention in dialysis patients.
Yoshikawa D, et al. Int J Cardiol. 2013 May 25;165(3):533-6. doi: 10.1016/j.ijcard.2011.09.078. - Circulating cathepsin K as a potential novel biomarker of coronary artery disease.
Yoshikawa D, et al. Atherosclerosis. 2013 May;228(1):211-6. doi: 10.1016/j.atherosclerosis.2013.01.004. - Serum albumin and C-reactive protein levels predict clinical outcome in hemodialysis patients undergoing endovascular therapy for peripheral artery disease.
Yoshikawa D, et al. Atherosclerosis. 2013 Mar;227(1):130-4. doi: 10.1016/j.atherosclerosis.2012.11.034. - Association of cardiac valvular calcifications and C-reactive protein with cardiovascular mortality in incident hemodialysis patients: a Japanese cohort study.
Yoshikawa D, et al. Am J Kidney Dis. 2013 Feb;61(2):254-61. doi: 10.1053/j.ajkd.2012.09.007. - Renal dysfunction and atherosclerosis of the neointima following bare metal stent implantation.
Yoshikawa D, et al. Am J Nephrol. 2013;38(1):58-65. doi: 10.1159/000353097. - Long-term outcome of drug-eluting vs. bare-metal stents in patients with acute myocardial infarction. Subgroup analysis of the nagoya acute myocardial infarction study (NAMIS).
Yoshikawa D, et al. Circ J. 2013;77(8):2024-31. doi: 10.1253/circj.cj-13-0017. - Impact of chronic kidney disease on a re-percutaneous coronary intervention for sirolimus-eluting stent restenosis.
Yoshikawa D, et al. Coron Artery Dis. 2012 Dec;23(8):528-32. doi: 10.1097/MCA.0b013e3283599463. - Relation between estimated glomerular filtration rate and composition of coronary arterial atherosclerotic plaques.
Yoshikawa D, et al. Am J Cardiol. 2012 Apr 15;109(8):1131-6. doi: 10.1016/j.amjcard.2011.11.052. - Impact of chronic kidney disease on the incidence of peri-procedural myocardial injury in patients undergoing elective stent implantation.
Yoshikawa D, et al. Nephrol Dial Transplant. 2012 Mar;27(3):1059-63. doi: 10.1093/ndt/gfr411. - Acute myocardial infarction caused by an anomalous left main coronary artery in a 16-year-old boy.
Yoshikawa D, et al. J Cardiol Cases. 2011 Oct 20;5(1):e55-e57. doi: 10.1016/j.jccase.2011.09.009. - Disruption of atherosclerotic neointima as a cause of very late stent thrombosis after bare metal stent implantation.
Yoshikawa D, et al. Am J Cardiol. 2012 Feb 1;109(3):448-9. doi: 10.1016/j.amjcard.2011.09.035. - Impact of plaque burden in the left main coronary artery determined by intravascular ultrasound on cardiovascular events in a Japanese population undergoing percutaneous coronary intervention.
Yoshikawa D, et al. Am J Cardiol. 2012 Feb 1;109(3):352-8. doi: 10.1016/j.amjcard.2011.09.021. - Effects of carperitide on contrast-induced acute kidney injury with a minimum volume of contrast in chronic kidney disease patients.
Yoshikawa D, et al.
Nephron Extra. 2012 Jan;2(1):303-10. doi: 10.1159/000345483. - Impact of metabolic syndrome on various aspects of microcirculation and major adverse cardiac events in patients with ST-segment elevation myocardial infarction.
Yoshikawa D, et al. Circ J. 2012;76(8):1972-9. doi: 10.1253/circj.cj-11-1299. - Percutaneous coronary intervention with bare metal stent vs. drug-eluting stent in hemodialysis patients.
Yoshikawa D, et alCirc J. 2012;76(7):1609-15. doi: 10.1253/circj.cj-12-0078. - Impact of low levels of vascular endothelial growth factor after myocardial infarction on 6-month clinical outcome. Results from the Nagoya Acute Myocardial Infarction Study.
Yoshikawa D, et al. Circ J. 2012;76(6):1509-16. doi: 10.1253/circj.cj-11-1127. - Sirolimus-eluting stent vs. everolimus-eluting stent for coronary intervention in patients on chronic hemodialysis.
Yoshikawa D, at al. Circ J. 2012;76(2):351-5. doi: 10.1253/circj.cj-11-0814. - Atorvastatin 10 mg plus ezetimibe 10mg compared with atorvastatin 20 mg: impact on the lipid profile in Japanese patients with abnormal glucose tolerance and coronary artery disease.
Yoshikawa D, et al. J Cardiol. 2012 Jan;59(1):50-6. doi: 10.1016/j.jjcc.2011.09.001. - Ankle brachial pressure index but not brachial-ankle pulse wave velocity is a strong predictor of systemic atherosclerotic morbidity and mortality in patients on maintenance hemodialysis.
Yoshikawa D, et al. Atherosclerosis. 2011 Dec;219(2):643-7. doi: 10.1016/j.atherosclerosis.2011.09.037. - Cystatin C: a possible sensitive marker for detecting potential kidney injury after computed tomography coronary angiography.
Yoshikawa D, et al. J Comput Assist Tomogr. 2011 Mar-Apr;35(2):240-5. doi: 10.1097/RCT.0b013e31820a9465. - Comparison of atorvastatin 5 and 20 mg/d for reducing F-18 fluorodeoxyglucose uptake in atherosclerotic plaques on positron emission tomography/computed tomography: a randomized, investigator-blinded, open-label, 6-month study in Japanese adults scheduled for percutaneous coronary intervention.
Yoshikawa D, et al. Clin Ther. 2010 Dec;32(14):2337-47. doi: 10.1016/j.clinthera.2010.12.001. - Volumetric analysis of coronary plaque characterization in patients with metabolic syndrome using 64-slice multi-detector computed tomography.
Yoshikawa D, et al. Circ J. 2010 Oct;74(10):2146-51. doi: 10.1253/circj.cj-10-0219. - Impact of acarbose on carotid intima-media thickness in patients with newly diagnosed impaired glucose tolerance or mild type 2 diabetes mellitus: A one-year, prospective, randomized, open-label, parallel-group study in Japanese adults with established coronary artery disease.
Yoshikawa D, et al. Clin Ther. 2010 Aug;32(9):1610-7. doi: 10.1016/j.clinthera.2010.07.015.
おわりに
医療は専門的で難しくなりがちですが、
少しでも安心して受診につなげられるような情報発信を心がけています。
心電図や胸部レントゲンのことで不安になったときに、
「ここを見れば少しわかる」、「ちょっと安心できる」、
と思ってもらえたら嬉しいです。
医療機関の方へ
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医療機関向けの掲載案内も行っております。
▷医療機関の方はこちらをご覧ください。